GramJS

const { Api, TelegramClient } = require("telegram");
const { StringSession } = require("telegram/sessions");

const session = new StringSession(""); // You should put your string session here
const client = new TelegramClient(session, apiId, apiHash, {});

(async function run() {
  await client.connect(); // This assumes you have already authenticated with .start()

  const result = await client.invoke(
    new Api.messages.SendMultiMedia({
      peer: "username",
      multiMedia: [
        new Api.InputSingleMedia({
          media: new Api.InputMediaUploadedPhoto({
            file: await client.uploadFile({
              file: new CustomFile(
                "file.bin",
                fs.statSync("../file.bin").size,
                "../file.bin"
              ),
              workers: 1,
            }),
            stickers: [
              new Api.InputDocument({
                id: BigInt("-4156887774564"),
                accessHash: BigInt("-4156887774564"),
                fileReference: Buffer.from("arbitrary data here"),
              }),
            ],
            ttlSeconds: 43,
          }),
          randomId: BigInt("-4156887774564"),
          message: "Hello there!",
        }),
      ],
      noforwards: true,
      scheduleDate: 43,
      sendAs: "username",
    })
  );
  console.log(result); // prints the result
})();

import { Api, TelegramClient } from "telegram";
import { StringSession } from "telegram/sessions";

const session = new StringSession(""); // You should put your string session here
const client = new TelegramClient(session, apiId, apiHash, {});

(async function run() {
  await client.connect(); // This assumes you have already authenticated with .start()

  const result: Api.Updates = await client.invoke(
    new Api.messages.SendMultiMedia({
      peer: "username",
      multiMedia: [
        new Api.InputSingleMedia({
          media: new Api.InputMediaUploadedPhoto({
            file: await client.uploadFile({
              file: new CustomFile(
                "file.bin",
                fs.statSync("../file.bin").size,
                "../file.bin"
              ),
              workers: 1,
            }),
            stickers: [
              new Api.InputDocument({
                id: BigInt("-4156887774564"),
                accessHash: BigInt("-4156887774564"),
                fileReference: Buffer.from("arbitrary data here"),
              }),
            ],
            ttlSeconds: 43,
          }),
          randomId: BigInt("-4156887774564"),
          message: "Hello there!",
        }),
      ],
      noforwards: true,
      scheduleDate: 43,
      sendAs: "username",
    })
  );
  console.log(result); // prints the result
})();