GramJS

const { Api, TelegramClient } = require("telegram");
const { StringSession } = require("telegram/sessions");

const session = new StringSession(""); // You should put your string session here
const client = new TelegramClient(session, apiId, apiHash, {});

(async function run() {
  await client.connect(); // This assumes you have already authenticated with .start()

  const result = await client.invoke(
    new Api.messages.UploadMedia({
      peer: "username",
      media: new Api.InputMediaUploadedPhoto({
        file: await client.uploadFile({
          file: new CustomFile(
            "file.bin",
            fs.statSync("../file.bin").size,
            "../file.bin"
          ),
          workers: 1,
        }),
        stickers: [
          new Api.InputDocument({
            id: BigInt("-4156887774564"),
            accessHash: BigInt("-4156887774564"),
            fileReference: Buffer.from("arbitrary data here"),
          }),
        ],
        ttlSeconds: 43,
      }),
    })
  );
  console.log(result); // prints the result
})();

import { Api, TelegramClient } from "telegram";
import { StringSession } from "telegram/sessions";

const session = new StringSession(""); // You should put your string session here
const client = new TelegramClient(session, apiId, apiHash, {});

(async function run() {
  await client.connect(); // This assumes you have already authenticated with .start()

  const result: Api.MessageMedia = await client.invoke(
    new Api.messages.UploadMedia({
      peer: "username",
      media: new Api.InputMediaUploadedPhoto({
        file: await client.uploadFile({
          file: new CustomFile(
            "file.bin",
            fs.statSync("../file.bin").size,
            "../file.bin"
          ),
          workers: 1,
        }),
        stickers: [
          new Api.InputDocument({
            id: BigInt("-4156887774564"),
            accessHash: BigInt("-4156887774564"),
            fileReference: Buffer.from("arbitrary data here"),
          }),
        ],
        ttlSeconds: 43,
      }),
    })
  );
  console.log(result); // prints the result
})();